LYME DISEASE, PREGNANCY AND MONTHLY HEARTWORM
Mary C. Wakeman, D.V.M.
Ashford Animal Clinic
Canine Fertility Center
Ashford, CT
Let's start this discussion with the big word and get it out of the way.
Jarisch-Herxheimer Reaction; Herxheimer or Herks for short.When the body
is harboring a significant amount of foreign protein, for instance, as
in the form of migrating heartworm larvae, migrating larvae of intestinal
worms, or the very large spirochaete bacteria that cause Lyme disease,
it is faced with a set of problems which cause disease (such as Lyme).
When those living organisms die, due to treatment with monthly heartworm
medication (any of the monthly meds) or due to treatment of Lyme disease
with a good antibiotic, the body reacts differently to the dead protein
in its tissues and blood stream. The dead spirochaetes may not be causing
symptoms of Lyme any longer, but they now cause an extreme inflammatory
response in the individual. The migrating larvae of intestinal parasites
usually do no great amount of harm while live, but when dead they, too,
cause a massive inflammatory reaction. Killing intestinal parasites as
adults does not entail any such risk. Likewise, killing heartworm stages
with the daily heartworm medications causes no risk of this nature.
The Herxheimer reaction in those of us who have Lyme disease usually
manifests itself as feeling really 'sick' one to five days after starting
on antibiotic medication, or after starting a different antibiotic medication,
and often periodically while continuing on the same medication. This is
taken clinically as proof that the disease is still active, and that the
antibiotic is effective as well. So there is something good about feeling
bad under these circumstances.
The exact same thing happens in dogs. The manifestations of Lyme disease
in dogs are exactly the same as in humans. Anything from headache, feeling
'sick', kidney malfunction, heart arrythmias, stiff neck, headache, muscle
and nerve pain, and joint pain can be affecting your dog.
How do you know if your dog has a headache?
One day a Dane bitch walked into my office with feet swollen to about
3 times normal size. She had had her monthly heartwormer the day before,
and her feet were swollen with edema due to the massive inflammatory reaction
she had to the dead protein of intestinal parasites she was host to.
So, the point of all of this is, what happens to the pregnant bitch if
she has this kind of reaction. What happens to sperm if the stud dog gets
monthly heartworm and also harbors intestinal parasites. These are some
of the matters which have led a significant number of veterinarians to
say 'no' to monthly heartwormers. 'No' to all of them, since the precise
chemical isn't the problem, but the very mechanism of action of this form
of heartworm control. All of those 'monthlies' which advertise control
of intestinal parasites are actually saying they can cause this kind of
problem.
When a new medication comes on the market, we are supposed to ask three
questions:
a.. 1. Is it more effective?
b.. 2. Is it safer?
c.. 3. Is it cheaper?
Monthly heartworm medication gets a 'no' response to each of these questions.
Is it good for your vet's bottom line? Well, that one gets a 'yes'. The
rule for breeding animals, dogs or bitches is no monthly heart worm medication.
What about Lyme disease in pregnant bitches? We are strongly suggesting
a Lyme Western Blot test in bitches before they are bred. First, Lyme
disease can be transmitted to the baby from the mother. Second, the antibiotic
medications we are most likely to prescribe to the pregnant bitch - due
to their known safety in pregnancy - are Amoxicillin and Cephalexin (Keflex).
These are also effective antibiotics for treating Lyme disease. Use of
these good antibiotics can precipitate a Herxheimer reaction in the pregnant
bitch with subclinical Lyme, disease which can cause resorption of fetuses.
Ask yourself this; how many litters have been lost in the past 15 years
in areas with Lyme disease due to Herxheimer reactions in pregnant bitches
with Lyme
disease? How many stud dogs have wiped out their sperm for a period of
6 weeks following treatment with a monthly heartwormer? How many pregnant
bitches are given monthly heartworm medication?
Our recommendations are:
No monthly heartworm medication ever in breeding animals. Lyme Western
Blot blood tests should be performed on bitches 4 to 6 weeks before they
are due in heat.
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ICED WATER
A BIG NO NO FOR OUR FURY FRIENDS
“...In surgery the doctor found that Baran's stomach was in its
normal anatomic position. The Doctor and I went over the events of what
happened up to the point of Baran's Bloating. When I told him about the
ice water he asked why I gave him ice water, and have I always did this.
I told him my history behind this practice and his reply was "I have
been very lucky for the past 15 years." The ice water I gave Baran
cause violent Muscle spasm in his stomach which caused the bloating. Even
though I figured his temp was down enough to feed and give him this ice
water his internal temp was still high.
Dr. Vogf stated that giving dog's ice to chew or ice water is a big
NO, NO; there should be not reason for them to have ice/ice water.
Normal water (room Temp.), or cooling with cold towels on the inter thigh.
This is the best way to help cool a dog. How Dr. Vogf
explained it to me was like this: If you as a person fall into a
frozen lake what happens to our muscles?
Think about that, then compare that to your dog's stomach.”
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